Clinical effect of platelet rich plasma in the treatment of periodontal intrabony defects. systematic review and meta-analysis
J. oral res. (Impresa)
; 6(4): 97-104, Apr. 2017. tab, ilus
Article
in English
| LILACS
| ID: biblio-907723
Responsible library:
CL30.1
ABSTRACT
Introduction:
One of the consequences of periodontitis is periodontal intrabony defects (PID). Various biomaterials have been used for its treatment, but there is still no biomaterial considered as the gold standard. Current research is focused on the use of platelet-rich plasma (PRP) for the treatment of PID.Objective:
To determine the clinical effect of PRP in the treatment of PID through a systematic review with meta-analysis. Materials andMethods:
A literature search was conducted until February 2017 in the biomedical databases Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS, IBECS, and the Cochrane Central Register of Clinical Trials. The criteria for the selection of the studies, which were randomized clinical trials, were the following articles or papers published in the last 5 years, reporting clinical effects, with a follow-up time equal to or greater than 6 months, and a sample size equal to or greater than 10 patients reporting the use of PRP as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference.Results:
The search strategy yielded nine articles reporting a reduction in probing depth and gingival recession, and an increase in clinical insertion level when using PRP alone or in combination with another biomaterial.Conclusion:
The reviewed literature suggests that the use of PRP in the treatment of PID has a positive clinical effect.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Periodontitis
/
Alveolar Bone Loss
/
Platelet-Rich Plasma
Type of study:
Controlled clinical trial
/
Systematic review
Language:
English
Journal:
J. oral res. (Impresa)
Journal subject:
Dentistry
Year:
2017
Document type:
Article
Affiliation country:
Peru
Institution/Affiliation country:
Universidad Católica los Ángeles de Chimbote/PE
/
Universidad Nacional de Trujillo/PE
/
Universidad Particular de Chiclayo/PE
/
Universidad Privada Antonio Guillermo Urrelu/PE
/
Universidad San Martín de Porres/PE
/
Universidad Señor de Sipán/PE