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Evaluation of cross reactivity between Trypanosoma cruzi and Leishmania infantum in serologically ineligible blood donors due to chagas diseas
Ferreira-Silva, Márcia Maria; Carvalho, Silvio Fernando Guimarães; Lula, Jamille Fernandes; Teles, Leandro de Freitas; Basques, Fernando Valadares; Teixeira, Luciana Almeida Silva; Tibúrcio, Monique Gomes Sales; Moraes-Souza, Helio.
Affiliation
  • Ferreira-Silva, Márcia Maria; Universidade Federal do Triângulo Mineiro. Uberaba. BR
  • Carvalho, Silvio Fernando Guimarães; Universidade Estadual de Montes Claros. Montes Claros. BR
  • Lula, Jamille Fernandes; Universidade Estadual de Montes Claros. Montes Claros. BR
  • Teles, Leandro de Freitas; Universidade Estadual de Montes Claros. Montes Claros. BR
  • Basques, Fernando Valadares; Fundação Hemominas. Montes Claros. BR
  • Teixeira, Luciana Almeida Silva; Universidade Federal do Triângulo Mineiro. Uberaba. BR
  • Tibúrcio, Monique Gomes Sales; Universidade Federal de Lavras. Lavras. BR
  • Moraes-Souza, Helio; Universidade Federal do Triângulo Mineiro. Uberaba. BR
Rev. patol. trop ; 46(1): 113-119, abr. 2017. tab
Article in English | LILACS | ID: biblio-913450
Responsible library: BR816.9
ABSTRACT
Inconclusive serological screening for Trypanosoma cruzi has been a problem for blood banks. This study examined the performance of serological techniques for Chagas disease in reagent samples from blood bank screenings and verified the possibilities of cross reactivity with visceral leishmaniasis. 68 samples of reagent donors tested with ELISA for Chagas disease were evaluated by other techniques and for the detection of anti-Leishmania antibodies. Four donors (5.9%) with positive results for T. cruzi were positive for ELISA Kalazar Detect (visceral leishmaniasis),three of which were confirmed by Western blot. This study confirms the specificity of the tests for Chagas disease in blood banks and reinforces the urgent adoption of measures to assess the real risk of transfusion transmission of visceral leishmaniasis
Subject(s)

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Full text: Available Collection: International databases Health context: Neglected Diseases Health problem: Chagas Disease / Neglected Diseases Database: LILACS Main subject: Chagas Disease Language: English Journal: Rev. patol. trop Journal subject: Tropical Medicine / Pathology Year: 2017 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Hemominas/BR / Universidade Estadual de Montes Claros/BR / Universidade Federal de Lavras/BR / Universidade Federal do Triângulo Mineiro/BR
Fulltext
Add to My VHL
Print
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Full text: Available Collection: International databases Health context: Neglected Diseases Health problem: Chagas Disease / Neglected Diseases Database: LILACS Main subject: Chagas Disease Language: English Journal: Rev. patol. trop Journal subject: Tropical Medicine / Pathology Year: 2017 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Hemominas/BR / Universidade Estadual de Montes Claros/BR / Universidade Federal de Lavras/BR / Universidade Federal do Triângulo Mineiro/BR