Ineffectiveness for Infants of Immunization of Mothers with Pneumococcal Capsular PolysaccharideVaccine During Pregnancy
Braz. j. infect. dis
; 1(13): 68-70, feb. 2009.
Article
in English
| Coleciona SUS, COGERH-Producao, Sec. Munic. Saúde SP, SAOLUIZGONZAGA-Producao, Sec. Munic. Saúde SP, Sec. Munic. Saúde SP
| ID: biblio-944796
Responsible library:
BR2105
Localization: BR2105
ABSTRACT
Pneumococcal (Pnc) carriage is associated with pneumococcal diseases. Breast feeding and maternal vaccinationmay be a useful approach to prevent pneumococcal infection in young infants. We examined the risk of Pnc carriageby infants at six months of age after pneumococcal polysaccharide vaccination of pregnant women. We selected 139pregnant woman. The woman were randomly allocated to receive 23-valent polysaccharide vaccines during pregnancy(Group 1) after pregnancy (Group 2) or not receive any vaccine (Group 3). Nasopharyngeal swabs were collectedfrom the infants at three and six months of age. The infants were evaluated monthly during the first six months. Weincluded 47 mothers in Group 1, 45 mothers in Group 2 and 47 mothers in Group 3. Forty-seven percent of the babieswere exclusively breast fed until six months, 26% received both breast feeding and artificial feeding and 13%received only artificial feeding. Among those patients, 26% were colonized by Pnc at six months (12 from group 1,13 from group 2, and 12 from group 3). There was no significant difference in colonization between the three groups.Thirty percent of the children were colonized by a non-susceptible strain. We concluded that young infants (threemonths old) are already susceptible to pneumococcal carriage. Vaccination during pregnancy with a polysaccharidevaccine did not decrease Pnc colonization.
Full text:
Available
Collection:
National databases
/
Brazil
Health context:
SDG3 - Target 3.3 End transmission of communicable diseases
Health problem:
Pneumonia
Database:
COGERH-Producao
/
SAOLUIZGONZAGA-Producao
/
Sec. Munic. Saúde SP
/
Coleciona SUS
Main subject:
Pneumonia, Pneumococcal
Limits:
Humans
/
Pregnancy
Language:
English
Journal:
Braz. j. infect. dis
Year:
2009
Document type:
Article
Institution/Affiliation country:
Santa Casa de Misericórdia de São Paulo/BR
/
Secretaria Municipal da Saúde/BR