Gastos do Ministério da Saúde do Brasil com medicamentos de alto Custo: uma análise centrada no paciente / Expenses of the Brazilian Ministry of Health for high-cost drugs: a demographic and clinical analysis

ABSTRACT

Objective:To describe the expenses of the Ministry of Health of Brazil with users of High-Cost Drug Program that began treatment between2000 –2004, according to their demographic and clinical characteristics.Methods:We made a probabilistic-deterministic linkage of nationaldata bases of drugs and mortality, resulting in a historical cohort ofpatients using high-cost medications in 2000 –2004. The per capitas pending on medicines were stratified by a follow-up period and de-scribed according to demographic, clinical and type of drug used. Results: The total population atended by the program was 611,419, being 63.5% female, average age 46 years. 41.9% of patients living in the Southeast and 29.7% in the North east of Brazil. 24.5% of patients began treatment in 2000, 12.4% in 2001, with increasing trend until 2004. The most prevalent diagnosis referred to the genitourinary system diseases and the most common use of chemical groups were antianemic prep-arations. 40,941 deaths were detected (6.7% of total). The total expen-diture per capita was R$4.794,34. Higher spending per capita was observed in males, aged 47, who lived in the Southeast of Brazil and began treatment in 2000, had diagnoses of infectious and parasitic diseases and used blood substitutes and perfusions solutions. Conclusion: Theunder standing of the expenses involved subsidizes restructuring actions and scheduling drug programs, also provides information for therapeutic groups which are priorities for analysis.