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Case for diagnosis. Erythroderma as manifestation of hypereosinophilic syndrome
Merlotto, Maira Renata; Cantadori, Lucas Oliveira; Sakabe, Delmo; Miot, Hélio Amante.
Affiliation
  • Merlotto, Maira Renata; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Department of Dermatology. Botucatu. BR
  • Cantadori, Lucas Oliveira; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Department of Clinical Medicine. Botucatu. BR
  • Sakabe, Delmo; Pontifícia Universidade Católica de São Paulo. Department of Surgery. Sorocaba. BR
  • Miot, Hélio Amante; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Department of Dermatology. Botucatu. BR
An. bras. dermatol ; 93(3): 451-453, May-June 2018. tab, graf
Article in English | LILACS | ID: biblio-949877
Responsible library: BR1.1
ABSTRACT
Abstract Hypereosinophilic syndrome is defined as persistent eosinophilia (>1500/µL for more than six months) associated with organ involvement, excluding secondary causes. It is a rare, potentially lethal disease that should be considered in cutaneous conditions associated with hypereosinophilia. We report a case of erythroderma as a manifestation of hypereosinophilic syndrome. A 36-year-old male with no comorbidities presented progressive erythroderma, pruritus, peripheral neuropathy, and eosinophilia in the previous seven months. No mutations were found in FIP1L1/PDGFRA. Patient experienced rapid remission in response to oral prednisone and hydroxyurea. Cutaneous manifestations may be the only evidence of hypereosinophilic syndrome. Genotyping excludes myeloproliferative disease, thereby orienting treatment and prognosis.
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: Dermatitis, Exfoliative / Hypereosinophilic Syndrome Type of study: Diagnostic study / Prognostic study Limits: Adult / Humans / Male Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2018 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Pontifícia Universidade Católica de São Paulo/BR / Universidade Estadual Paulista/BR

Full text: Available Collection: International databases Database: LILACS Main subject: Dermatitis, Exfoliative / Hypereosinophilic Syndrome Type of study: Diagnostic study / Prognostic study Limits: Adult / Humans / Male Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2018 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Pontifícia Universidade Católica de São Paulo/BR / Universidade Estadual Paulista/BR
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