Case for diagnosis. Erythroderma as manifestation of hypereosinophilic syndrome
An. bras. dermatol
; 93(3): 451-453, May-June 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-949877
Responsible library:
BR1.1
ABSTRACT
Abstract Hypereosinophilic syndrome is defined as persistent eosinophilia (>1500/µL for more than six months) associated with organ involvement, excluding secondary causes. It is a rare, potentially lethal disease that should be considered in cutaneous conditions associated with hypereosinophilia. We report a case of erythroderma as a manifestation of hypereosinophilic syndrome. A 36-year-old male with no comorbidities presented progressive erythroderma, pruritus, peripheral neuropathy, and eosinophilia in the previous seven months. No mutations were found in FIP1L1/PDGFRA. Patient experienced rapid remission in response to oral prednisone and hydroxyurea. Cutaneous manifestations may be the only evidence of hypereosinophilic syndrome. Genotyping excludes myeloproliferative disease, thereby orienting treatment and prognosis.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Dermatitis, Exfoliative
/
Hypereosinophilic Syndrome
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2018
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Pontifícia Universidade Católica de São Paulo/BR
/
Universidade Estadual Paulista/BR