Fibrosis pulmonar aguda asociada a intoxicación por Paraquat: caso clínico / Acute pulmonary fibrosis associated with Paraquat poisoning: report of one case
Rev. méd. Chile
; 146(7): 938-941, jul. 2018. tab, graf
Article
in Spanish
| LILACS
| ID: biblio-961482
Responsible library:
CL1.1
ABSTRACT
Paraquat, a non-selective bipyridyl pesticide, is one of the leading causes of death from intoxication in many parts of Asia and America. It is the second most sold herbicide worldwide, being widely used in Chile. Its ingestion generates toxicity due to the release of superoxide radicals, mainly affecting kidneys, lungs and liver. There is no antidote available. We report a 31 years old male who ingested Paraquat for suicidal purposes. He developed an acute renal and hepatic failure and a rapidly progressive severe respiratory failure with images compatible with acute pulmonary fibrosis. No response to immunosuppressive treatment was observed. He died eight days after admission. The use of cyclophosphamide associated with glucocorticoids could lower risk of death the in these patients, although the pathophysiology of respiratory failure is still under study.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Paraquat
/
Pulmonary Fibrosis
/
Herbicides
Type of study:
Risk factors
Limits:
Adult
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2018
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Clínica Las Condes/CL
/
Universidad Finis Terrae/CL