The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults
J. infect
; 72(4): 408-438, Apr. 2016.
Article
in English
| BIGG - GRADE guidelines
| ID: biblio-966151
Responsible library:
BR1.1
ABSTRACT
Bacterial meningitis and meningococcal sepsis are rare conditions with high case fatality rates. Early recognition and prompt treatment saves lives. In 1999 the British Infection Society produced a consensus statement for the management of immunocompetent adults with meningitis and meningococcal sepsis. Since 1999 there have been many changes. We therefore set out to produce revised guidelines which provide a standardised evidence-based approach to the management of acute community acquired meningitis and meningococcal sepsis in adults. A working party consisting of infectious diseases physicians, neurologists, acute physicians, intensivists, microbiologists, public health experts and patient group representatives was formed. Key questions were identified and the literature reviewed. All recommendations were graded and agreed upon by the working party. The guidelines, which for the first time include viral meningitis, are written in accordance with the AGREE 2 tool and recommendations graded according to the GRADE system. Main changes from the original statement include the indications for pre-hospital antibiotics, timing of the lumbar puncture and the indications for neuroimaging. The list of investigations has been updated and more emphasis is placed on molecular diagnosis. Approaches to both antibiotic and steroid therapy have been revised. Several recommendations have been given regarding the follow-up of patients.
Full text:
Available
Collection:
Tematic databases
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
BIGG - GRADE guidelines
Main subject:
Meningitis, Bacterial
/
Sepsis
/
Meningococcal Infections
Type of study:
Diagnostic study
/
Practice guideline
/
Prognostic study
Language:
English
Journal:
J. infect
Year:
2016
Document type:
Article
Institution/Affiliation country:
British Infection Society/GB