Influence of tramadol on functional recovery of acute spinal cord injury in rats
Acta cir. bras
; 33(12): 1087-1094, Dec. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-973483
Responsible library:
BR1.1
ABSTRACT
Abstract Purpose:
To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats.Methods:
Ten rats were divided into two groups (n = 5). All animals were submitted by a laminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn't receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods.Results:
There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group.Conclusion:
The tramadol as an analgesic agent don't influence on functional recovery of acute spinal cord injury in rats
Full text:
Available
Collection:
International databases
Health context:
Sustainable Health Agenda for the Americas
Health problem:
Goal 9: Noncommunicable diseases and mental health
Database:
LILACS
Main subject:
Spinal Cord Injuries
/
Tramadol
/
Recovery of Function
/
Analgesics, Opioid
Type of study:
Evaluation study
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2018
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
CESUPA/BR
/
Centro Universitário do Estado do Pará/BR
/
UEPA/BR
/
UFRA/BR
/
Universidade Federal Rural da Amazônia/BR
/
Universidade Federal do Pará/BR
/
Universidade do Estado do Pará/BR