Re-emergence of human T-lymphotropic viruses in West Africa
Braz. j. infect. dis
; 22(3): 224-234, May-June 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-974211
Responsible library:
BR1.1
ABSTRACT
ABSTRACT Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers. A total of 2626 references were initially retrieved using search terms Worldwide prevalence of HTLV, HTLV in Africa, HTLV in West Africa, HTLV subtypes, HTLV 3 and 4 in Africa, HTLV of African origin, HTLV seroindeterminate results, Spread of HTLV. These references were rigorously trimmed down to 76. Although evidence shows that HTLV is still endemic in the region, West Africa lacks recent epidemiological prevalence data. Thorough investigations are needed to ascertain the true cause of indeterminate Western Blot results. It is imperative that routine screening for HTLVs be mandated in West African health care facilities.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Deltaretrovirus Infections
/
Deltaretrovirus
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
/
Systematic review
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Africa
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2018
Document type:
Article
Affiliation country:
Nigeria
/
Pakistan
Institution/Affiliation country:
Ahmadu Bello University/NG
/
COMSATS University/PK