Ameloblastoma with distinctive granular cell pattern: an 8 case study
Autops. Case Rep
; 8(4): e2018052, Oct.-Dec. 2018. ilus
Article
in English
| LILACS
| ID: biblio-986609
Responsible library:
BR26.7
ABSTRACT
Ameloblastoma with granular cell pattern (AGC) is classified as an unusual histological subtype of solid/multicystic ameloblastoma, characterized by granular changes in stellate-like cells located within the inner portion of the epithelial follicles. Studies have revealed that lysosomal overload causes cytoplasmic granularity; however, the mechanism involved remains poorly understood. Here we report on eight cases of granular cell ameloblastoma, in the posterior region of the mandible. The age of the patients included in this case series ranged from 35 -64 years old and 87.5% of cases occurred in non-Caucasians, with a slight gender predilection for men (62.5%). There was no evidence of recurrence, and the majority of the cases were treated with surgical resection (87.5%). All tumors displayed histopathological features consistent with the diagnosis of ameloblastoma with granular cell pattern.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Ameloblastoma
/
Jaw Neoplasms
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Autops. Case Rep
Journal subject:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Year:
2018
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
AC Camargo Cancer Center/BR
/
Universidade de São Paulo/BR