Factores sociodemográficos y fisiopatológicos asociados a la tuberculosis del sistema nervioso central en un Hospital Público de Lima-Perú, 2014-2017 / Sociodemographic and physiopathological factors associated with tuberculosis of the central nervous system in a Public Hospital of Lima-Peru, 2014-2017
Infectio
; 23(2): 155-160, abr.-jun. 2019. tab, graf
Article
in Spanish
| LILACS, COLNAL
| ID: biblio-989946
Responsible library:
CO359.1
RESUMEN
Objetivo:
Determinar los factores sociodemográficos y fisiopatológicos de la neurotuberculosis (NTB) en los pacientes registrados en el Programa de Control de la Tuberculosis (PCT) del Hospital Nacional Dos de Mayo. Materiales yMétodos:
Se realizó un estudio transversal analítico, desarrollado entre Julio del 2014 y Julio del 2017. Se diseñó una ficha que incluyó datos sociodemográficos, fisiopatológicos y las características al diagnóstico. Se obtuvieron las razones de prevalencia (RP) crudos y ajustados, con intervalos de confianza al 95%.Resultados:
Participaron 1038 pacientes. El 16% de toda la población y de 34% de las tuberculosis extra pulmonares tenia NTB. La forma clínica más frecuente fue la meningoencefalitis tuberculosa (MEC TB) (96%). Dentro de las manifestaciones clínicas destacaron las convulsiones (22%), cefalea (20%), signos meníngeos (18%) y trastorno del sensorio (16%). La presencia de NTB estuvo asociada al diagnóstico de VIH (RPa 2,06; IC95% 1,53-2,76; Valor p<0,001), condición de alcoholismo (RPa 1,53; IC95% 1,04-2,25; Valor p=0,030) y género femenino (RPa 1,40; IC95% 1,06-1,84; Valor p=0,019).Conclusiones:
El diagnóstico de VIH, condición de alcoholismo y el género femenino son factores asociados a mayor frecuencia de NTB en el Hospital Dos de Mayo.ABSTRACT
Objective:
To determine the sociodemographic and physiopathological factors of neurotuberculosis (NTB) in the patients registered in the Tuberculosis Control Program (TCP) of the Hospital Nacional Dos de Mayo. Materials andMethods:
Analytical cross- sectional study, developed between July 2014 and 2017 July. We designed a card that included data sociodemographic, pathophysiological and the diagnostic characteristics. Were obtained prevalence ratio (RP) raw and adjusted, with 95% confidence intervals.Results:
1038 patients participated. 16% of the entire population and 34% of the extrapulmonary tuberculosis had NTB. The most common clinical form was tuberculous meningoencephalitis (MEC TB) (96%). Within the clinical manifestations emphasized the seizures (22%), headache (20%), meningeal signs (18%) and sensory disorder (16%). The presence of NTB was associated with the diagnosis of HIV (aPR 2.06, 95%CI 1.53-2.76, P value <0.001), alcoholism (aPR 1.53, 95%CI 1.04-2.25, p value = 0.030) and female gender (aPR 1.40, 95%CI 1.06-1.84, p value = 0.019).Conclusions:
The diagnosis of HIV, condition of alcoholism and the female gender are factors associated with increased frequency of NTB in the Hospital Dos de Mayo.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
/
SDG3 - Target 3.3 End transmission of communicable diseases
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
/
SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5
Health problem:
Target 3.3: End transmission of communicable diseases
/
Target 3.2: Reduce avoidable death in newborns and children under 5
/
Neglected Diseases
/
Tuberculosis
/
Meningitis
/
Tuberculosis
/
Other Respiratory Diseases
/
Infections
/
Noncommunicable Diseases
Database:
COLNAL
/
LILACS
Main subject:
Respiratory Tract Infections
/
Demography
/
Epidemiological Monitoring
Type of study:
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
/
Screening study
Aspects:
Social determinants of health
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
South America
/
Colombia
/
Peru
Language:
Spanish
Journal:
Infectio
Journal subject:
Communicable Diseases
Year:
2019
Document type:
Article
Affiliation country:
Peru
Institution/Affiliation country:
Universidad Continental/PE
/
Universidad Ricardo Palma/PE