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Factores sociodemográficos y fisiopatológicos asociados a la tuberculosis del sistema nervioso central en un Hospital Público de Lima-Perú, 2014-2017 / Sociodemographic and physiopathological factors associated with tuberculosis of the central nervous system in a Public Hospital of Lima-Peru, 2014-2017
Vera, Claudia A; Patron-Ordoñez, Gino; Verastegui-Diaz, Araseli; Mejia, Christian R.
Affiliation
  • Vera, Claudia A; Universidad Ricardo Palma. Facultad de Medicina. Lima. PE
  • Patron-Ordoñez, Gino; Universidad Ricardo Palma. Facultad de Medicina. Lima. PE
  • Verastegui-Diaz, Araseli; Universidad Ricardo Palma. Facultad de Medicina. Lima. PE
  • Mejia, Christian R; Universidad Continental. Coordinación de Investigación. Huancayo. PE
Infectio ; 23(2): 155-160, abr.-jun. 2019. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-989946
Responsible library: CO359.1
RESUMEN

Objetivo:

Determinar los factores sociodemográficos y fisiopatológicos de la neurotuberculosis (NTB) en los pacientes registrados en el Programa de Control de la Tuberculosis (PCT) del Hospital Nacional Dos de Mayo. Materiales y

Métodos:

Se realizó un estudio transversal analítico, desarrollado entre Julio del 2014 y Julio del 2017. Se diseñó una ficha que incluyó datos sociodemográficos, fisiopatológicos y las características al diagnóstico. Se obtuvieron las razones de prevalencia (RP) crudos y ajustados, con intervalos de confianza al 95%.

Resultados:

Participaron 1038 pacientes. El 16% de toda la población y de 34% de las tuberculosis extra pulmonares tenia NTB. La forma clínica más frecuente fue la meningoencefalitis tuberculosa (MEC TB) (96%). Dentro de las manifestaciones clínicas destacaron las convulsiones (22%), cefalea (20%), signos meníngeos (18%) y trastorno del sensorio (16%). La presencia de NTB estuvo asociada al diagnóstico de VIH (RPa 2,06; IC95% 1,53-2,76; Valor p<0,001), condición de alcoholismo (RPa 1,53; IC95% 1,04-2,25; Valor p=0,030) y género femenino (RPa 1,40; IC95% 1,06-1,84; Valor p=0,019).

Conclusiones:

El diagnóstico de VIH, condición de alcoholismo y el género femenino son factores asociados a mayor frecuencia de NTB en el Hospital Dos de Mayo.
ABSTRACT

Objective:

To determine the sociodemographic and physiopathological factors of neurotuberculosis (NTB) in the patients registered in the Tuberculosis Control Program (TCP) of the Hospital Nacional Dos de Mayo. Materials and

Methods:

Analytical cross- sectional study, developed between July 2014 and 2017 July. We designed a card that included data sociodemographic, pathophysiological and the diagnostic characteristics. Were obtained prevalence ratio (RP) raw and adjusted, with 95% confidence intervals.

Results:

1038 patients participated. 16% of the entire population and 34% of the extrapulmonary tuberculosis had NTB. The most common clinical form was tuberculous meningoencephalitis (MEC TB) (96%). Within the clinical manifestations emphasized the seizures (22%), headache (20%), meningeal signs (18%) and sensory disorder (16%). The presence of NTB was associated with the diagnosis of HIV (aPR 2.06, 95%CI 1.53-2.76, P value <0.001), alcoholism (aPR 1.53, 95%CI 1.04-2.25, p value = 0.030) and female gender (aPR 1.40, 95%CI 1.06-1.84, p value = 0.019).

Conclusions:

The diagnosis of HIV, condition of alcoholism and the female gender are factors associated with increased frequency of NTB in the Hospital Dos de Mayo.
Subject(s)


Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / Neglected Diseases / SDG3 - Target 3.3 End transmission of communicable diseases / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Target 3.3: End transmission of communicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Neglected Diseases / Tuberculosis / Meningitis / Tuberculosis / Other Respiratory Diseases / Infections / Noncommunicable Diseases Database: COLNAL / LILACS Main subject: Respiratory Tract Infections / Demography / Epidemiological Monitoring Type of study: Observational study / Prevalence study / Prognostic study / Risk factors / Screening study Aspects: Social determinants of health Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: South America / Colombia / Peru Language: Spanish Journal: Infectio Journal subject: Communicable Diseases Year: 2019 Document type: Article Affiliation country: Peru Institution/Affiliation country: Universidad Continental/PE / Universidad Ricardo Palma/PE

Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / Neglected Diseases / SDG3 - Target 3.3 End transmission of communicable diseases / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Target 3.3: End transmission of communicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Neglected Diseases / Tuberculosis / Meningitis / Tuberculosis / Other Respiratory Diseases / Infections / Noncommunicable Diseases Database: COLNAL / LILACS Main subject: Respiratory Tract Infections / Demography / Epidemiological Monitoring Type of study: Observational study / Prevalence study / Prognostic study / Risk factors / Screening study Aspects: Social determinants of health Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: South America / Colombia / Peru Language: Spanish Journal: Infectio Journal subject: Communicable Diseases Year: 2019 Document type: Article Affiliation country: Peru Institution/Affiliation country: Universidad Continental/PE / Universidad Ricardo Palma/PE
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