Terpenoids isolated from Azadirachta indica roots and biological activities
Rev. bras. farmacogn
; 29(1): 40-45, Jan.-Feb. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-990765
Responsible library:
BR1.1
ABSTRACT
Abstract The chemical study of roots from Azadirachta indica A. Juss., Meliaceae, led to the isolation of two new terpenoids, limonoid morenolide and diterpene 17-hydroxy-sandaracopimar-8,15-dien-11-one, in addition to the four well-known limonoids nimbinene, nimbinal, nimbandiol and salannin, and three diterpenoids nimbidiol, ferruginol, and 6,7-dehydroferruginol. Their structural elucidations were based on one and bidimensional Nuclear Magnetic Resonance and Electrospray ionization mass spectrometry spectra data which was compared to the data found in literature. The anti-inflammatory, cytotoxic and antimycobacterial activities of the identified terpenoids were evaluated.
Full text:
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Collection:
International databases
Database:
LILACS
Language:
English
Journal:
Rev. bras. farmacogn
Journal subject:
Pharmacy
Year:
2019
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Federal de Santa Catarina Campus Criciúma/BR
/
Universidade Estadual do Norte Fluminense Darcy Ribeiro/BR