An in Vitro Evaluation of Remineralizing Capacity of Self-Assembling Peptide (SAP) P11-4 and Casein Phosphopeptides-Amorphous Calcium Phosphate (CPP-ACP) on Artificial Enamel
Pesqui. bras. odontopediatria clín. integr
; 19(1): 4504, 01 Fevereiro 2019. tab, graf
Article
in English
| LILACS, BBO - Dentistry
| ID: biblio-997972
Responsible library:
BR1264.1
ABSTRACT
Objective:
To determine and compare the remineralizing capacity of self-assembling peptide (SAP) P11-4 and casein phosphopeptidesamorphous calcium phosphate (CPP-ACP) on enamel. Material andMethods:
Enamel samples were divided into 2 groups. Group I was treated with Selfassembling peptide (SAP) P11-4 and group II with casein phosphopeptides-amorphous calcium phosphate (CPP-ACP). In both groups, remineralizing capacity was assessed at baseline, 2 weeks, 6 weeks and 12 weeks. Student's t- test and ANOVA were applied, with the significance level set at 5%.Results:
The mean calcium weight % was evaluated at baseline, 2 weeks, 6 weeks and 12 weeks. In Group I, there was increase in mean value (62.12 ± 1.24) from baseline to 12 weeks (67.36 ± 2.14). However, there was decrease in phosphate weight % from 37.16 ± 2.52 at baseline to 35.72 ± 2.11 at 12 weeks. In Group II, mean calcium weight % was 64.18 ± 1.52 at baseline, which ultimately increased to 66.01 ± 2.03 at 12 weeks. Phosphate weight % showed reduction from 37.34 ± 2.23 at baseline to 35.04 ± 2.02 at 12 weeks. Ca/P ratio showed significant improvement. There was significant difference in Ca/P ratio at 2 weeks, 6 weeks and 12 weeks in both groups (p<0.05).Conclusion:
Self-assembling peptide (SAP) P11-4 found to be more effective and efficient as compared to casein phosphopeptidesamorphous calcium phosphate (CPP-ACP).
Full text:
Available
Collection:
International databases
Database:
BBO - Dentistry
/
LILACS
Main subject:
Phosphopeptides
/
Tooth Remineralization
/
In Vitro Techniques
/
Caseins
/
Dental Enamel
Limits:
Adolescent
/
Adult
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2019
Document type:
Article