In Situ Effect of Intra-Oral Application of Pastes Containing CPP-ACP or CPP-ACPF Against Initial Enamel Erosion
Pesqui. bras. odontopediatria clín. integr
; 19(1): 4785, 01 Fevereiro 2019. tab
Article
in English
| LILACS, BBO - Dentistry
| ID: biblio-998223
Responsible library:
BR1264.1
ABSTRACT
Objective:
To evaluate in situ the effect of toothpastes containing casein phosphopeptide - amorphous calcium phosphate (CPP-ACP) and casein phosphopeptide-amorphous calcium phosphate associated to fluoride (CPP-ACPF) on initial erosion prevention. Material andMethods:
Bovine enamel blocks (n = 192) were randomly assigned into 4 phases according to the baseline surface hardness GI CPP-ACP Paste (MI Paste™), GII CPP-ACPF Paste (MI Paste Plus™), GIII Fluoridated paste and GIV Placebo Paste. In each of the 4 crossover phases, twelve volunteers wore intraoral palatal appliances containing 4 enamel blocks for 2 hours, then the tested treatments were applied intraorally (3 min) and the appliance was maintained in the mouth for another 3 hours. After, the appliances were removed and immersed in hydrochloric acid (0.01 M, pH 2.3) for 30 seconds to promote erosive demineralization. The final surface hardness was evaluated and percentage of surface hardness loss was calculated. The data were analyzed by ANOVA and Tukey's test (α = 5%).Results:
The application of CPP-ACP paste, independent of fluoride content, resulted in significant lower enamel hardness loss (GI 9.26% ±3.48 and GII 9.14% ±1.73) compared to NaF (GIII 15.5% ± 3.94) and placebo (GIV 16.7% ± 4.07) pastes, which did not show difference between them.Conclusion:
The CPP-ACP pastes were able to reduce initial erosive demineralization in relation to fluoride and placebo pastes. Nevertheless the formulation of CPP-ACP with fluoride did not provide an additional benefit.
Full text:
Available
Collection:
International databases
Database:
BBO - Dentistry
/
LILACS
Main subject:
Tooth Erosion
/
Toothpastes
/
Calcium Fluoride
/
Tooth Demineralization
Type of study:
Controlled clinical trial
/
Evaluation study
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2019
Document type:
Article