Detección de un complejo clonal con el genotipo de Brucella abortus biovariedad 2 como fundador en aislamientos de B. abortus de Argentina. / [Detection of a clonal complex with Brucella abortus biovar 2 genotype as founder in B. abortus isolates from Argentina].
Rev. Argent. Microbiol.
; 45(4): 229-39, 2013 Oct-Dec.
Article
in Spanish
| BINACIS
| ID: bin-132756
ABSTRACT
Brucella abortus is the causative agent of bovine brucellosis, a worldwide zoonosis. Up to date, eight biovars of B. abortus have been described. In Argentina, biovar 1 is the most frequently isolated. However, biovar 2, which is more pathogenic than biovar 1, is also found. Molecular methods for subtyping isolates are necessary for allowing epidemiological surveillance and control of eradication programs. Due to the genetic homogeneity of the genus Brucella, the development of molecular typing tools has been difficult. The publication of microorganism genomes facilitates the design of this approach. The aim of this work was to employ a Multiple Locus VNTR Analysis (MLVA) scheme for strains from Argentina isolated in our laboratory. From the 56 isolates analyzed, 47 different genotypic profiles were obtained. All the strains typed as biovar 2 showed the same profile. This scheme allowed assigning each isolate to the biovar it belongs to. All the genotypes were related using the goeBURST analysis and biovar 2 was proposed as founder.
Search on Google
Collection:
National databases
/
Argentina
Health context:
Neglected Diseases
Health problem:
Zoonoses
Database:
BINACIS
Main subject:
Brucella abortus
Type of study:
Diagnostic study
Country/Region as subject:
South America
/
Argentina
Language:
Spanish
Journal:
Rev. Argent. Microbiol.
Year:
2013
Document type:
Article