Diseminación de blaIMP-8 en enterobacterias aisladas en un hospital de Buenos Aires / [Dissemination of blaIMP-8 among Enterobacteriaceae isolates from a Buenos Aires Hospital].
Rev. argent. microbiol
; 45(2): 104-9, jun. 2013.
Article
in Spanish
| LILACS, BINACIS
| ID: biblio-1171777
Responsible library:
AR5.1
Localization: [{"text": "AR5.1"}]
RESUMO
From August 2008 to December 2011, six metallo-ß-lactamase-producing isolates, four Enterobacter cloacae, one Klebsiella oxytoca and one Citrobacter freundii, were detected at Hospital Interzonal General de Agudos "Evita" in Lanús. All six isolates showed multiresistant profiles and the presence of the blaIMP-8 gene. Five isolates also expressed PER-2 extended spectrum ß-lactamase. The blaIMP-8 gene was found as the first cassette in a class 1 integron. However, the 3´ conserved sequence could not be detected in three isolates. In all cases, blaIMP-8 was transferred by conjugation to azide-resistant Escherichia coli J53. PFGE analysis revealed that the four E. cloacae isolates were not genetically related. These are the first metallo-ß-lactamases detected in this institution and our results suggest a possible intra- and inter-species horizontal dissemination of blaIMP-8.
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Collection:
International databases
/
National databases
/
Argentina
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
BINACIS
/
LILACS
Main subject:
Beta-Lactamases
/
Enterobacteriaceae
Limits:
Aged, 80 and over
Country/Region as subject:
South America
/
Argentina
Language:
Spanish
Journal:
Rev. Argent. Microbiol.
/
Rev. argent. microbiol
Journal subject:
Microbiology
Year:
2013
Document type:
Article