Association between the Asthma Predictive Index and levels of exhaled nitric oxide in infants and toddlers with recurrent wheezing. / Association between the Asthma Predictive Index and levels of exhaled nitric oxide in infants and toddlers with recurrent wheezing.
Arch Argent Pediatr
; 111(3): 191-5, 2013 Jun.
Article
in Es
| BINACIS
| ID: bin-133109
ABSTRACT
It is difficult to make an early identification of which children with recurrent wheezing will develop asthma in the following years. The Asthma Predictive Index (API) is a questionnaire based on clinical and laboratory parameters used for this end. The measurement of fractional exhaled nitric oxide (FE NO) has been used as a marker of eosinophilic airway infammation in asthma patients. Objective. To determine the association between the Asthma Predictive Index and FE NO levels in children younger than 3 years old with recurrent wheezing. Materials and methods. Observational, cross sectional study. Children younger than 36 months old with 3 or more episodes of bronchial obstruction in the past year who were inhaled corticosteroid-naive or leukotriene receptor antagonist-naive were included. After recording clinical data, FE NO was measured by a chemiluminescence analyzer during tidal breathing (online method). Results. A total of 52 children aged 5-36 months old were included. Patients with a positive API accounted for 60
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Collection:
06-national
/
AR
Database:
BINACIS
Main subject:
Asthma
/
Respiratory Sounds
/
Nitric Oxide
Type of study:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Language:
Es
Journal:
Arch Argent Pediatr
/
Arch. argent. pediatr
/
Arch. argent. pediatr. (En línea)
/
Archivos argentinos de pediatría
Year:
2013
Document type:
Article
Country of publication:
Argentina