Sensibilidad del equipo Cobas AmpliScreenÔäó HIV-1 Test, v1.5, para la detección de HIV-1. / [Sensitivity of the COBAS AmpliScreenÔäó HIV-1 test v1.5 for HIV-1 detection].
Rev. Argent. Microbiol.
; 46(3): 196-200, 2014 Jul-Sep.
Article
in Spanish
| BINACIS
| ID: bin-133302
ABSTRACT
The introduction of nucleic acid amplification techniques (NAT) in blood banks was intended to reduce the residual risk of transfusion-transmitted infections. Co-circulation of a great diversity of HIV-1 variants in Argentina portrays the need to assess the sensitivity of serological and molecular assays available for their detection. In this study, we evaluated the sensitivity of the COBAS AmpliScreen HIV-1 Test, version 1.5 (Roche) for the detection of HIV-1 RNA in plasma samples of infected individuals from Argentina. The results of this study reveal that this technique has high sensitivity for the detection of HIV-1 RNA under assay conditions using mini-pool testing, pools  50 RNA copies per ml achieved  92
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Collection:
National databases
/
Argentina
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.3 End transmission of communicable diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Sepsis
Database:
BINACIS
Main subject:
Viremia
/
RNA, Viral
/
HIV Infections
/
HIV-1
/
Colorimetry
/
Reverse Transcriptase Polymerase Chain Reaction
Type of study:
Diagnostic study
/
Screening study
Country/Region as subject:
South America
/
Argentina
Language:
Spanish
Journal:
Rev. Argent. Microbiol.
Year:
2014
Document type:
Article