Isometric developed tension and histopathology of myocardium of chagasic mice. II.
Acta Physiol. Pharmacol. Ther Latinoam
; 42(3): 197-204, 1992.
Article
in English
| BINACIS
| ID: bin-37889
Responsible library:
AR1.1
ABSTRACT
In a preceding paper we reported the evolution of chagasic cardiopathy in mice inoculated with low number of T. cruzi from 2 days to 75 days post-infection (p.i.). The present work analyzed the contractility, pharmacological response and histopathology of myocardium isolated from chronic chagasic mice from 90 days until 180 days. p.i. Myocardium contractile force reached values similar to controls until 165 days p.i. From this to the end contractility was significantly lower. At 90 days p.i. NE provoked negative inotropic effect or had no effect in 13
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Collection:
National databases
/
Argentina
Health context:
Neglected Diseases
Health problem:
Chagas Disease
Database:
BINACIS
Language:
English
Journal:
Acta Physiol. Pharmacol. Ther Latinoam
Year:
1992
Document type:
Article