Cardiopatía chagasica: identificación y cuantificación de células infiltrantes, en corazones de pacientes que sufrieron muerte cardíaca a distintas edades. / [Chagas cardiopathy: identification and quantification of infiltrating cells in the hearts of cardiac death patients of different ages]

ABSTRACT

The purpose of this work was to obtain new data on factors intervening in the production and progression of human chagasic cardiopathy (HChC) with death by cardiac failure. We studied cardiac samples of patients that died at an early mean age versus others that died at older ages. The infiltrating cells were characterized and quantified by means of specific monoclonal antibodies and inmunohistochemical methodology; and by classical histological and histochemical methods. We found intense cardiac infiltration by lymphocytes that reacted with the antibodies anti-CD45RO against activated T-lymphocytes (< 70