Prototipo de fuente lumínica para terapia fotodinámica diseñado en el Centro de Microscopía Electrónica. / [Prototype of light source for photodynamic therapy in Centre of Electron Microscopy]

ABSTRACT

The Photodynamic Therapy (PDT) is a cancer treatment based on specific accumulation of a photosensitizer in the malignant tissue and its subsequent irradiation at appropriate wave lengths induce the production of oxygen singlets responsible for peroxidation of cell organelles and cell death. A prototype of a 630 nm non coherent light source designed and constructed at the Centre of Electron Microscopy of The Cordoba National University allowed a successful application of PDT, in nonmelanoma skin tumors, for the first time in this Country. A topical treatment with 20