Medición del filtrado glomerular con Tc99m DTPA. Comparación de métodos. / [Glomerular filtration rate with Tc99m DTPA. Comparison of methods]

ABSTRACT

Glomerular filtration rate (GFR) is an important index of renal function. The aim of this study was to compare the GFR with 99m Tc. DTPA without urine collection estimated with three, two and single-sample methods. We studied 148 patients (54 women and 94 men, 3-84 years old) with diverse renal diseases. After intravenous administration of Tc99m DTPA three (90-120-180 min. Method 1; n = 44) or two (120 and 180 min or 180 and 240 min Method 2, n = 104) blood samples were taken. The GFR (ml/min) were calculated using monoexponential analysis, or with only the sample of the 180 or 240 min with the methods of Jacobsson, Russel, Groth-Aasted, Dakubu and Constable. RESULTS: 1) In 37/148 (25