Metabolismo de benzodiacepinas en distintos modelos de hepatopatías experimentales. / [Benzodiazepines metabolism in various models of experimental liver diseases]
Acta gastroenterol. latinoam
; 29(1): 3-7, 1999.
Article
in Spanish
| BINACIS
| ID: bin-39987
Responsible library:
AR40.1
ABSTRACT
The aim of the present paper is to establish possible disturbances in benzodiazepines glucuronidation in two experimental models of liver injury paracetamol acute intoxication and cholestasis followed by paracetamol acute intoxication. We concluded that, despite the alterations observed in liver microsomal lipid profile, glucuronidation remained similar to controls in paracetamol intoxicated rats. On the contrary, cholestatic animals followed by paracetamol intoxication showed an increment in the glucuronidation of the utilized substrated.
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Collection:
National databases
/
Argentina
Database:
BINACIS
Language:
Spanish
Journal:
Acta gastroenterol. latinoam
Year:
1999
Document type:
Article