Effect of streptozotocin-diabetes on thymus of normal and adrenalectomized rats.

ABSTRACT

The injection of streptozotocin in intact or adrenalectomized rats produced a decrease in the number of thymus lymphoid cells. Bovine serum albumin gradient analyses of thymocytes from control, adrenalectomized, adrenalectomized-diabetic and diabetic animals showed variations in the mature/immature cell ratio. No remarkable changes in the distribution of the different thymocyte subpopulations were observed.