Regression of AIDS-related Kaposis sarcoma following combined antiretroviral treatment
Rev. argent. microbiol
; 32(4): 206-208, oct.-dec. 2000.
Article
in English
| BINACIS
| ID: bin-6743
Responsible library:
BR1.1
ABSTRACT
The aim of the study was to assess regression of Kaposis sarcoma (KS) in AIDS patients in Argentina. Eighteen male AIDS patients with human immunodeficiency virus (HIV)-associated Kaposis sarcoma at different clinical stages received KS specific treatment and/or anti-retroviral therapy. Triple anti-retroviral therapy was given to most of the patients with the exception of four who received zidovudine (ZDV) in combination with another nucleoside analogue but no protease inhibitors. Plasma viral load and CD4+ T lymphocyte number were measured in two blood samples (before and after treatment). Complete remission was found in all patients (five) at KS stage I, three out of eight patients at stage II but in none at stages III and IV. Two out of three patients at KS stage IV did not respond to treatments at all. Three patients at KS stages I and II showed complete remission of sarcoma with only anti-retroviral therapy suggesting that anti-retroviral therapy and non-KS specific chemotherapy can successfully control KS.(AU)
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Collection:
National databases
/
Argentina
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
BINACIS
Main subject:
Sarcoma, Kaposi
/
Acquired Immunodeficiency Syndrome
/
Anti-HIV Agents
Limits:
Adult
/
Aged
/
Humans
/
Male
Language:
English
Journal:
Rev. argent. microbiol
Year:
2000
Document type:
Article
Institution/Affiliation country:
SIDA+Argentina