The clinical and histological spectrum of esophagitis in pediatrics. Some keys to its links to gastritis
Acta gastroenterol. latinoam
; 31(3): 143-147, 2001. ilus, tab
Article
in En
| BINACIS
| ID: bin-8913
Responsible library:
BR1.1
ABSTRACT
The purpose of our study was to assess the clinical and histological spectrum of esophagitis, seeking possible links between esophagitis and gastritis particularly Helicobacter pylori-associated, in pediatric patients. MATERIAL AND METHODS:
We retrospectively studied 66 sequential and 63 gastric biopsies from 66 patients fulfilling the histological diagnosis of "esophagitis". Cases were arranged in two groups G1 (H. pylori negative) N = 44 (27 m; 17 f), mean age 7.3 y (range 7-9 m-18 y) and G2 (H. pylori positive) N = 22 (16 f; 6 m), mean age 12.8 y (range 7-16 y).RESULTS:
The bases for performing endoscopy and biopsies were as follows in G1 (N44) symptoms of gastroesophageal reflux (GER) in 24 cases and non-GER in 20 cases; in G2 (N = 22) symptoms of GER in 13 and non-GER in 9 cases. Esophageal endoscopic findings for G1 patients included normal mucosa 39; esophagitis 3; congestive mucosa and esophagitis 1 each. Stomach endoscopic findings for G1 patients were normal mucosa 29; nodular antrum 7; congestive mucosa 4; ulceration 2; unknown 2. G2 children revealed nodular antrum 19; congestive antrum 2; normal mucosa 1. Histology of esophageal biopsies in G1 was esophagitis grade 1,35; grade 2,4; grade 3, 4, and grade 5, 1. G2 showed esophagitis grade 1,20, and grade 2,2. The histologic findings of the gastric biopsies were as follows G1 (N = 41) normal mucosa 23; mild chronic gastritis 6; mucus depletion in the superficial 5; mild acute gastritis 3; hemorrhage 1; insufficient tissue 3. G2 chronic gastritis associated with H. pylori with or without follicular hyperplasia 21; mild gastritis 1. (AU)
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Collection:
06-national
/
AR
Database:
BINACIS
Main subject:
Helicobacter pylori
/
Helicobacter Infections
/
Esophagitis
/
Gastritis
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Acta gastroenterol. latinoam
Year:
2001
Document type:
Article