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Efecto de la lesión de la sustancia negra parte compacta sobre la liberación de glutamato y GABA en el núcleo pedunculopontino / The effects of lesions in the compact part of the substantia nigra on glutamate and GABA release in the pedunculopontine nucleus
Blanco Lezcano, L; Rocha Arrieta, LL; Alvarez González, L; Martínez Martí, L; Pavón Fuentes, N; González Fraguela, ME; Bauzá Calderín, Y; Coro Grave de Peralta, Y.
Affiliation
  • Blanco Lezcano, L; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
  • Rocha Arrieta, LL; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
  • Alvarez González, L; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
  • Martínez Martí, L; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
  • Pavón Fuentes, N; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
  • González Fraguela, ME; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
  • Bauzá Calderín, Y; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
  • Coro Grave de Peralta, Y; Centro Internacional de Restauración Neurológica. Departamento de Neurofisiología Experimental. La Habana. Cuba
Rev Neurol ; 40(1)Jan. 2005.
Article in English | CUMED | ID: cum-40077
Responsible library: CU1.1
ABSTRACT
The pedunculopontine nucleus (PPN), co-localized with the mesencephalic locomotor region, has been proposed as a key structure in the physiopathology of Parkinson's disease.

OBJECTIVES:

The goal of the present study was to assess if the aminoacid neurotransmitter release in the PPN is modified by the degeneration of dopaminergic cells, from substantia nigra pars compacta in 6-hydroxidopamine (6-OHDA)-lesioned rats. In addition, it was studied the aminoacid neurotransmitter release in the PPN of rats with lesion of the subthalamic nucleus by quinolinic acid (QUIN) (100 nmol) intracerebral injection...(AU)
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Full text: Available Collection: National databases / Cuba Database: CUMED Main subject: Substantia Nigra / Glutamic Acid / Pedunculopontine Tegmental Nucleus / Gamma-Aminobutyric Acid Limits: Animals Language: English Journal: Rev Neurol Year: 2005 Document type: Article Institution/Affiliation country: Centro Internacional de Restauración Neurológica/Cuba
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Full text: Available Collection: National databases / Cuba Database: CUMED Main subject: Substantia Nigra / Glutamic Acid / Pedunculopontine Tegmental Nucleus / Gamma-Aminobutyric Acid Limits: Animals Language: English Journal: Rev Neurol Year: 2005 Document type: Article Institution/Affiliation country: Centro Internacional de Restauración Neurológica/Cuba