Linfocitos T CD4+ y carga viral en pacientes VIH/sida de la tercera edad que reciben tratamiento antirretroviral / CD4+ T-lymphocytes and viral load in elderly patients with HIV/AIDS who receive antiretroviral treatment
Rev. cuba. invest. bioméd
; 32(2)abr.-jun. 2013. tab, ilus
Article
in Es
| CUMED
| ID: cum-57020
Responsible library:
CU1.1
Localization: CU1.1
RESUMEN
Introducciín: La infección por el virus de inmunodeficiencia humana (VIH) constituye un importante problema de salud. La capacidad funcional del sistema inmune declina gradualmente con el envejecimiento. Objetivo: Demostrar que los pacientes VIH/sida de la tercera edad, tratados con antirretrovirales, presentan disminución de la carga viral y aumento de los linfocitos T CD4+ con el uso del tratamiento. Métodos: Se realizó un estudio observacional prospectivo de corte transversal en 44 pacientes VIH/SIDA pertenecientes al servicio de Medicina del IPK que recibieron tratamiento con diferentes esquemas de antirretrovirales. Resultados: Se observó un incremento medio de linfocitos T CD4+ de 97 cel/ÁL asó como una disminución media de carga viral de 3 583 cp/ÁL después del tratamiento anitrretroviral. Conclusiones: Con este estudio podemos concluir que con el uso de la terapia antirretroviral en los pacientes VIH/sida de la tercera edad aumentaron los linfocitos T CD4+ y disminuyó la carga viral, lo que evidencia la reconstitución inmunológica y el control virológico de estos pacientes(AU)
ABSTRACT
Background: Infection with the Human Immunodeficiency Virus (HIV) is a major health problem. The functional capacity of the immune system gradually declines with aging. Objective: To demonstrate that the elderly patients with HIV/AIDS who follow treatment with antiretroviral drugs present a fall in viral load and a rise in the CD4+ T-lymphocytes with this treatment. Methods: A cross-sectional prospective observational study was conducted in 44 HIV/AIDS patients attended in the Medical Services offered by IPK who received treatment with different antiretroviral schemes. Results: It was observed that there was an average rise of 97 cel/ÁL in the CD4+ T-lymphocytes, as well as an average fall of 3 583 cp/ÁL in viral load after the antiretroviral treatment. Conclusions: With this study, we can conclude that there was a rise in CD4+ T-lymphocytes and a fall in the viral load in the elderly patients with HIV/AIDS who followed treatment with antiretroviral drugs, what evidences the immunological reconstitution and virologic control of these patients with the use of antiretroviral therapy(AU)
Key words
Full text:
1
Collection:
06-national
/
CU
Database:
CUMED
Main subject:
CD4-Positive T-Lymphocytes
/
Acquired Immunodeficiency Syndrome
/
Lymphocyte Count
/
Anti-Retroviral Agents
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Caribe
/
Cuba
Language:
Es
Journal:
Rev. cuba. invest. bioméd
Year:
2013
Document type:
Article