Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore
Mem. Inst. Oswaldo Cruz
; 104(2): 133-148, mar. 2009. ilus
Article
in English
| HISA - History of Health
| ID: his-17233
Responsible library:
BR1.1
Localization: BR1273.1
ABSTRACT
The discovery of Toxoplasma gondii independently by Nicolle and Manceaux [1908] and Splendore [1908] was to open a 'Pandora's Box' that has led research on this parasite into a number os scientific disciplines. In the 100 years since its discovery, the mystery surrouding T. gondii and its inter-relationship with humans has continued to provide a stimulating source of material in many areas of research, resulting in the publiction of almost 20.000 papers and a number of books. This flood of diverse information shows no sign of abating, with an average of 10 papers per week appearing in PubMed. Herein, it is impossible to do more than provide a very superficial comment on what has become a massive body of scientific information. T. gondii has many unique features and seems to be the 'exception to almost every rule' thus acting as a focus for research in disciplines from epidemiology to immunology to human behaviour to cell biology to human disease. In this review a number of the historical advances will be mentioned and combined with a description of the basic biology of the parasite. [AU]
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Collection:
Tematic databases
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Neglected Diseases
/
Zoonoses
Database:
HISA - History of Health
Main subject:
Parasitology
/
Toxoplasma
/
Toxoplasmosis
/
Public Health
Aspects:
Social determinants of health
Country/Region as subject:
Europa
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Year:
2009
Document type:
Article
Institution/Affiliation country:
Oxford University/Reino Unido