Bioterápico 17DH de Trypanosoma cruzi diminui alterações histopatológicas em camundongos infectados pelo protozoário / Biotherapic of Trypanosoma cruzi 17x controlled histopathological alterations in mice infected by this protozoon

ABSTRACT

Introduction: about 10 million people worldwide suffer from Chagas? disease [1]. The World Health Organization (WHO) has explicitly acknowledged the significance of this condition and supports the use of Complementary and Alternative Medicine by health systems integrated with conventional treatments. Even so, one century after its discovery it still represents a global challenge [1,2]. Biotherapics are ultradiluted medicines and the infection of mice by Trypanosoma cruzi is an excellent model to understand their effect [3,4]. At 8 weeks, mice are physiologically more developed than at age 4 weeks, including a more competent immune system [5].Conclusion: there is a difference in the effect of the ultradiluted medicine between mice 4- and 8-week old. Eight-week old animals treated with biotherapic exhibited lower tissue parasitism, which is the opposite of what was observed in 4-week old animals.(AU)