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Fotodermatitis de contacto por dexketoprofeno. Descripción de dos casos / Photocontacs dermatitis due to dexketoprofen. Report of 2 cases
González-Pérez, R; Trébol, I; García-Ríos, I; Arregui, M. A; Soloeta-Arechavala, R.
Affiliation
  • González-Pérez, R; Hospital Santiago Apóstol. Vitoria. España
  • Trébol, I; Hospital Santiago Apóstol. Vitoria. España
  • García-Ríos, I; Hospital Santiago Apóstol. Vitoria. España
  • Arregui, M. A; Hospital Santiago Apóstol. Vitoria. España
  • Soloeta-Arechavala, R; Hospital Santiago Apóstol. Vitoria. España
Actas dermo-sifiliogr. (Ed. impr.) ; 97(7): 456-459, sept. 2006. ilus, tab
Article in Es | IBECS | ID: ibc-048054
Responsible library: ES1.1
Localization: ES1.1 - BNCS
RESUMEN
El dexketoprofeno es el isómero activo del ketoprofeno y como aquél pertenece al grupo de antiinflamatorios no esteroideos (AINE) derivados del ácido propiónico. Recientemente hemos estudiado con parches y fotoparches a dos mujeres con una clínica característica de fotodermatitis de contacto que habían usado los días previos dexketoprofeno tópico (Enangel®). En ambos casos se empleó la batería estándar del GEIDC, una batería de AINE, el producto propio (Enangel®) y sus excipientes. En las dos pacientes se observaron a las 96 horas fotoparches positivos frente a dexketoprofeno y Enangel®. Además, en una de ellas se evidenciaron fotosensibilizaciones simultáneas a otros AINE y a varios excipientes del Enangel®. Revisando la bibliografía, sólo hemos encontrado tres referencias sobre fotodermatitis de contacto por dexketoprofeno. Aportamos dos nuevos casos, en uno de los cuales se asociaron múltiples fotosensibilidades. Consideramos que estos pacientes deben parchearse con dexketoprofeno al 0,1-1 % vaselina, concentraciones sensiblemente inferiores a las usadas en publicaciones previas
ABSTRACT
Dexketoprofen is the active isomer of ketoprofen and likewise belongs to the group of non-steoidal anti-inflammatory drugs (NSAIDs) derived from propionic acid. We have recently studied, using patch and photopatch tests, two women with a characteristic clinical picture of contact photodermatitis who had used topical dexketoprofen (Enangel®) in the days before onset of the rash. In both cases we used the standard series of GEIDC, a series for NSAIDs, the product itself (Enangel®) and its excipients. On examination of the photopatches of both patients at 96 hours we found positive reactions to dexketoprofen and Enangel®. Furthermore, in one of the women we observed simultaneous photosensitivity to other NSAIDs and to several excipients of Enangel®. Reviewing the literature we have found only three references on contact photodermatitis due to dexketoprofen. We describe two new cases, with multiple photosensitivities in one of them. We consider that such patients should be patch tested with dexketoprofen at 0.1-1 % petrolatum, concentrations that are notably inferior to those used in previous publications
Subject(s)
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Collection: National databases / Spain Database: IBECS Main subject: Photosensitivity Disorders / Fenofibrate / Anti-Inflammatory Agents, Non-Steroidal / Drug Eruptions Limits: Adult / Female / Humans Language: Spanish Journal: Actas dermo-sifiliogr. (Ed. impr.) Year: 2006 Document type: Article Institution/Affiliation country: Hospital Santiago Apóstol/España
Search on Google
Collection: National databases / Spain Database: IBECS Main subject: Photosensitivity Disorders / Fenofibrate / Anti-Inflammatory Agents, Non-Steroidal / Drug Eruptions Limits: Adult / Female / Humans Language: Spanish Journal: Actas dermo-sifiliogr. (Ed. impr.) Year: 2006 Document type: Article Institution/Affiliation country: Hospital Santiago Apóstol/España
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