Streptococcus agalactiae altamente resistente a fluoroquinolonas / Streptococcus agalactiae highly resistant to fluoroquinolones

RESUMEN

Antecedentes. Streptococcus agalactiae se mantiene sensible a la penicilina, si bien se ha descrito un incremento en la resistencia a otras familias de antimicrobianos como macrólidos y más raramente fluoroquinolonas. Métodos y resultados. Entre 2003 y 2004 se detectaron dos cepas de S. agalactiae resistentes a fluoroquinolonas, que presentaron mutaciones en parC (Ser79 → Phe) y gyrA (Glu85 → Ala o Glu85 → Lys). Conclusión. Se describen por primera vez en España cepas de S. agalactiae altamente resistentes a fluoroquinolonas (AU)

ABSTRACT

Background. Streptococcus agalactiae remains susceptible to penicillin; nevertheless, an increase in the resistance to other antimicrobial families, such as macrolides and more rarely fluoroquinolones, has been described. Methods and results. From 2003 to 2004, two fluoroquinolone-resistant S. agalactiae strains were detected. The strains presented one mutation in parC (Ser79 → Phe) and an additional mutation in gyrA (Glu85 → Ala or Glu85 → Lys). Conclusion. This study describes the first S. agalactiae strains highly resistant to fluoroquinolones in Spain (AU)