Incidencia del infarto agudo de miocardio en la evolución de los pacientes en tratamiento con diálisis / Incidence of acute myocardial infarction in the evolution of dialysis patients
Nefrología (Madr.)
; 32(5): 597-604, sept.-oct. 2012. ilus, tab
Article
in Spanish
| IBECS
| ID: ibc-106149
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
Introducción:
Aunque la frecuencia de la enfermedad coronaria (EAC) en los pacientes en diálisis se estima muy elevada, existe una gran variabilidad en los estudios en la tasa de infarto agudo de miocardio (IAM).Objetivo:
Establecer la incidencia IAM y analizar sus características y repercusión en la evolución de los pacientes incidentes en diálisis.Métodos:
Estudiamos los pacientes incidentes en diálisis entre el 1/1/1999 y el 31/12/2007, y analizamos la presentación del primer IAM en diálisis. Valoramos diagnósticos previos de diabetes, hipertensión arterial, EAC (IAM o lesiones en coronariografía), accidente cerebrovascular isquémico, arteriopatía periférica avanzada y tabaquismo. Se analizaron urea, creatinina, hematocrito, calcio/fósforo, hormona paratiroidea intacta, lípidos y albúmina. El seguimiento fue hasta trasplante, muerte, pérdida o cierre del estudio el 31/12/2010.Resultados:
De 576 pacientes incluidos (64,6 ± 16 años; 24,7% diabéticos; 82,3% hemodiálisis/17,7% diálisis peritoneal), 34 (5,9%) (..) (AU)ABSTRACT
Background:
Although the estimated frequency of coronary artery disease (CAD) in patients on dialysis is very high, there is considerable variation in the studies published to date regarding the rate of acute myocardial infarction (AMI) in these patients.Objective:
To establish the incidence of AMI and to analyse the characteristics and consequences of this entity on the clinical progression of incident dialysis patients.Methods:
We recorded AMI in the patients treated in our dialysis unit between 01/01/1999 and 31/12/07. The variables assessed were prior diagnosis of diabetes, hypertension, CAD (AMI or lesions observed in coronary angiography), ischaemic cerebrovascular accident, advanced peripheral artery disease (PAD), atrial fibrillation and tobacco use. Biochemical analyses included urea, creatinine, haematocrit, calcium, phosphorous, iPTH, lipids and albumin. Follow-up lasted until transplant, death, loss to follow-up or study end in Dec. 2010.Results:
Of the 576 patients recruited (aged 64.6±16 years), 24.7% had diabetes, 82.3% were on haemodialysis (17.7% on peritoneal dialysis), and 34 (5.9%) had a previous diagnosis of CAD. In a follow-up lasting a mean of 40.2±32 months (1931.5 patient-years), 40 patients (6.9%) suffered an AMI. The incidence was 2.13/100 patient-years. The patients without CAD had an incidence of 1.84/100 patient-years and those with a previous (..) (AU)
Full text:
Available
Collection:
National databases
/
Spain
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Cardiovascular Disease
/
Chronic Kidney Disease
/
Endocrine System Diseases
/
Ischemic Heart Disease
Database:
IBECS
Main subject:
Renal Dialysis
/
Renal Insufficiency, Chronic
/
Myocardial Infarction
Type of study:
Incidence study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Humans
Language:
Spanish
Journal:
Nefrología (Madr.)
Year:
2012
Document type:
Article
Institution/Affiliation country:
Complejo Hospitalario de Jaén/España