Importancia del screening de tuberculosis previo al tratamiento con inhibidores del factor de necrosis tumoral alfa / Importance of tuberculosis screening before inhibiting tumour necrosis factor-alpha therapy
Arch. Soc. Esp. Oftalmol
; 88(1): 36-39, ene. 2013. ilus
Article
in Spanish
| IBECS
| ID: ibc-109505
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
Introducción:
En los últimos años se ha registrado un aumento en la incidencia de infección tuberculosa, debido a la utilización cada vez mayor de fármacos inhibidores del factor de necrosis tumoral alfa (anti-TNF alfa) en el tratamiento de enfermedades inflamatorias. Caso clínico Se describe el caso de un varón en tratamiento con infliximab (anti-TNF alfa) que desarrolla tuberculosis diseminada con afectación ocular.Conclusión:
Es de gran importancia la realización de un screening apropiado para detectar pacientes con riesgo de desarrollar tuberculosis antes de iniciar tratamiento con dichos fármacos. Con este propósito, el QuantiFERON®-TB Gold in Tube (Interferon Gamma Release Assay, IGRA) se presenta como una alternativa de alta sensibilidad y especificidad(AU)ABSTRACT
Introduction:
There has been an increase in the incidence of tuberculosis infection in recent years, due to the increasing use of drugs inhibiting tumour necrosis factor-alpha (anti-TNF alpha) in the treatment of inflammatory diseases. Case report We report the case of a male patient being treated with infliximab (anti-TNF alpha) who developed disseminated tuberculosis with ocular involvement.Conclusion:
It is very important to conduct a proper screening to detect patients at risk for tuberculosis before starting treatment with these drugs. For this purpose, the QuantiFERON®-TB Gold in Tube (Interferon Gamma Release Assay, IGRA) is presented as an alternative screening test with high sensitivity and specificity(AU)
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Collection:
National databases
/
Spain
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Tuberculosis
Database:
IBECS
Main subject:
Tuberculosis, Ocular
/
Tumor Necrosis Factor-alpha
/
Receptors, Tumor Necrosis Factor
/
Granuloma
Type of study:
Diagnostic study
/
Screening study
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Arch. Soc. Esp. Oftalmol
Year:
2013
Document type:
Article
Institution/Affiliation country:
Hospital Universitario Central de Asturias/España