Hepatitis C aguda en un paciente en tratamiento con etanercept / Acute Hepatitis C in a Patient Receiving Etanercept
Actas dermo-sifiliogr. (Ed. impr.)
; 104(3): 239-241, abr. 2013. ilus
Article
in Spanish
| IBECS
| ID: ibc-111594
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
El uso de agentes bloqueadores del factor de necrosis tumoral alfa (anti-TNFα) en pacientes con hepatitis C crónica ha sido descrito en la literatura en su conjunto como seguro y eficaz. Sin embargo, no se han descrito hasta la fecha casos de primoinfección por el virus de la hepatitis C ocurridos durante el tratamiento con un biológico. Presentamos un paciente con psoriasis moderada-severa de larga evolución que, estando en tratamiento con etanercept, sufrió una hepatitis C aguda. Sin suspender el fármaco anti-TNFα recibió tratamiento con interferón pegilado, con respuesta virológica sostenida. Etanercept no interfirió de forma negativa en la evolución de la enfermedad ni en la respuesta al tratamiento antiviral (AU)
ABSTRACT
According to the literature, the use of tumor necrosis factor (TNF) inhibitors in patients with chronic hepatitis C infection is safe and effective. There have been no reports, however, of primary infection with the hepatitis C virus during treatment with a biologic agent. We report the case of a patient with long-standing moderate to severe psoriasis who developed acute hepatitis C while being treated with etanercept. Biologic therapy was continued and the infection was successfully treated with pegylated interferon, which achieved a sustained virologic response. Etanercept did not have a negative impact on disease outcome or on response to antiviral treatment (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Psoriasis
/
Biological Treatment
/
Methotrexate
/
Tumor Necrosis Factor-alpha
/
Hepatitis C
/
Adrenal Cortex Hormones
Limits:
Humans
/
Male
Language:
Spanish
Journal:
Actas dermo-sifiliogr. (Ed. impr.)
Year:
2013
Document type:
Article
Institution/Affiliation country:
Hospital Arnau de Vilanova/España