May T1 diabetes mellitus protect from asthma?
Allergol. immunopatol
; 41(5): 288-291, sept.-oct. 2013. tab, graf
Article
in English
| IBECS
| ID: ibc-116397
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Background:
Type 1 diabetes mellitus (T1DM) may be associated with allergy. It was previously reported that >20% of children with T1DM had allergic rhinitis (AR), but none was asthmatic. This finding was surprising as allergic rhinitis is frequently associated with asthma and asthma prevalence is about 10% of the general paediatric population. Thus, it was hypothesized that T1DM could protect from asthma.Objectives:
The aim of this preliminary study was to evaluate the pulmonary function and the response to bronchodilation testing in children, suffering from T1DM with associated AR, comparing them with a control group of children with AR alone.Methods:
Twenty children with T1DM and AR were compared with 59 children with AR alone; spirometry and bronchodilation testing were performed in all patients.Results:
There were no statistically significant differences in both at baseline and after bronchodilation testing about FVC, FEV1, and FEF2575 values. However, changes in post-bronchodilator values of FEF2575 (ΔFEF2575) were significantly higher in children with AR alone than in children with T1DM and AR (p = 0.04).Conclusions:
This preliminary study could sustain the hypothesis that T1DM in children suffering also from AR might exert a protective effect of preventing the possible evolution in asthma (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Asthma
/
Rhinitis, Allergic, Perennial
/
Diabetes Mellitus, Type 1
Type of study:
Risk factors
Limits:
Humans
Language:
English
Journal:
Allergol. immunopatol
Year:
2013
Document type:
Article
Institution/Affiliation country:
IRCCS Azienda Ospedaliera Universitaria San Martino/Italy
/
Istituto Giannina Gaslini/Italy