Dietary restriction improves systemic and muscular oxidative stress in type 2 diabetic Goto-Kakizaki rats

Rodrigues, Lisa; Crisóstomo, Joana; Matafome , Paulo; Louro, Teresa; Nunes, Elsa

Rodrigues, Lisa; Crisóstomo, Joana; Matafome , Paulo; Louro, Teresa; Nunes, Elsa.

Affiliation

Rodrigues, Lisa; Faculty of Medicine of University of Coimbra. Institute of Physiology. Coimbra. Portugal
Crisóstomo, Joana; Faculty of Medicine of University of Coimbra. Institute of Physiology. Coimbra. Portugal
Matafome , Paulo; Faculty of Medicine of University of Coimbra. Institute of Physiology. Coimbra. Portugal
Louro, Teresa; Faculty of Medicine of University of Coimbra. Institute of Physiology. Coimbra. Portugal
Nunes, Elsa; Faculty of Medicine of University of Coimbra. Institute of Physiology. Coimbra. Portugal

J. physiol. biochem ; 67(4): 613-619, dic. 2011.

Article in English | IBECS | ID: ibc-122399

Responsible library: ES1.1

Localization: BNCS

RESUMEN
ABSTRACT

RESUMEN

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ABSTRACT

Type 2 diabetes is a heterogeneous metabolic disease characterized by insulin resistance and Beta-cell dysfunction leading to hyperglycaemia and dyslipidaemia. Dietary intervention seems to improve some of these cellular complications, namely insulin resistance. Our aim was to evaluate the effects of dietary restriction on systemic and skeletal muscle oxidative stress and insulin resistance in normal Wistar rats and (..) (AU)

Subject(s)

Animals; Rats; Diabetes Mellitus, Type 2/physiopathology; Oxidative Stress; Fasting/physiology; Muscle, Skeletal/metabolism; Insulin-Secreting Cells/metabolism; Metabolic Syndrome/physiopathology

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Collection: National databases / Spain Database: IBECS Main subject: Fasting / Oxidative Stress / Diabetes Mellitus, Type 2 Limits: Animals Language: English Journal: J. physiol. biochem Year: 2011 Document type: Article Institution/Affiliation country: Faculty of Medicine of University of Coimbra/Portugal

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