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Effect of clenbuterol on apoptosis, adipogenesis, and lipolysis in adipocytes
Kim, Hye-Kyeong; Baile, Clifton A; Della-Fera, Mary Anne; Hausman, Dorothy B.
Affiliation
  • Kim, Hye-Kyeong; The Catholic University of Korea. Department of Food Science and Nutrition. Bucheon. South Korea
  • Baile, Clifton A; University of Georgia. Department of Animal and Dairy Science. Athens. USA
  • Della-Fera, Mary Anne; University of Georgia. Department of Animal and Dairy Science. Athens. USA
  • Hausman, Dorothy B; University of Georgia. Department of Foods and Nutrition. Athens. USA
J. physiol. biochem ; 66(3): 197-203, sept. 2010.
Article in En | IBECS | ID: ibc-122825
Responsible library: ES1.1
Localization: BNCS
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ABSTRACT
Clenbuterol, a beta2-adrenergic receptor (Beta2-AR) selective agonist, has been shown to decrease body fat in animals and can induce apoptosis in adipose tissue in mice. We hypothesized that direct actions of a Beta -adrenergic receptor agonist on adipocytes could trigger the observed apoptotic effect. The hypothesis was inspected by investigating the direct effect of clenbuterol on apoptosis,adipogenesis, and lipolysis in vitro using the 3T3-L1 cell line and rat primary adipocytes. Cells were treated with (…) (AU)
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Collection: 06-national / ES Database: IBECS Main subject: Clenbuterol / Apoptosis / Adipocytes / Adipogenesis / Lipolysis Limits: Animals Language: En Journal: J. physiol. biochem Year: 2010 Document type: Article
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Collection: 06-national / ES Database: IBECS Main subject: Clenbuterol / Apoptosis / Adipocytes / Adipogenesis / Lipolysis Limits: Animals Language: En Journal: J. physiol. biochem Year: 2010 Document type: Article