RARã and TRBeta expressions are decreased in PBMC and SWAT of obese subjects in weight gain
J. physiol. biochem
; 66(1): 29-37, mar. 2010.
Article
in English
| IBECS
| ID: ibc-122847
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
No disponible
ABSTRACT
In order to evaluate the expression of nuclear receptors at the peripheral level in obese subjects,messenger RNA (mRNA) levels of different isoforms of retinoic acid receptor (RAR), triiodothyronine(TR), and peroxisome proliferator-activated receptor (PPAR) were determined and compared in peripheral mononuclear blood cells (PBMC) and subcutaneous white adipose tissue (SWAT). Twelve lean subjects and 68 obese subjects divided into weight gain (WG), weight-stable (WS), and weight loss (WL) groups were studied. Nuclear receptor mRNA levels were assessed in PBMC and SWAT using a quantitative real-time reverse transcription polymerase chain (..) (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
RNA, Messenger
/
Leukocytes, Mononuclear
/
Obesity
Limits:
Humans
Language:
English
Journal:
J. physiol. biochem
Year:
2010
Document type:
Article
Institution/Affiliation country:
Université Bordeaux 1/France
/
Université Bordeaux/France