Wilms' tumour: a complex enigma to decipher
Clin. transl. oncol. (Print)
; 10(8): 457-461, ago. 2008. ilus
Article
in English
| IBECS
| ID: ibc-123481
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Wilms' tumour (WT) is the most common solid tumour of childhood. The molecular signalling pathways determining the origin and behaviour of WT are very complex and several genes in several loci may participate. This review tries to briefly compile recent works on the histology and on the molecular alterations that promote the genesis, development and behaviour of WT. Some molecular alterations seem to be associated with specific histological types and particular clinical outcomes, suggesting that they might be utilised to determine the prognosis and to identify poor prognostic subgroups that can be targeted for more individualised treatments (AU)
RESUMEN
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Abnormalities, Multiple
/
Genes, Wilms Tumor
/
Chromosome Aberrations
/
Wilms Tumor
/
Kidney Neoplasms
Type of study:
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2008
Document type:
Article
Institution/Affiliation country:
HH.UU Virgen del Rocío/Spain