Evaluation of toxicity of surgery and/or chemoirradiation treatment of uterine cervix cancer
Clin. transl. oncol. (Print)
; 11(2): 109-113, feb. 2009. tab
Article
in En
| IBECS
| ID: ibc-123587
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
OBJECTIVE: To evaluate acute and chronic toxicity of chemoirradiation treatment (neoadjuvant, adjuvant and radical treatment) in patients diagnosed with cervix cancer. METHODS: From December 1999 to August 2007, 53 patients diagnosed with adenocarcinoma or squamous cell carcinoma of the uterine cervix received neoadjuvant, adjuvant or radical chemoirradiation. RESULTS: Acute gastrointestinal toxicity of grade 3 or more in 9 patients (17%) and haematological toxicity of grade 3 or more in 9 patients (17%). Chronic toxicity of grade 3 or more was shown in only 2 patients (4%). The most frequent toxicities were gastrointestinal toxicity and haematological toxicity. The most frequent chronic toxicities were gastrointestinal toxicity and vaginal toxicity. CONCLUSIONS: We report that the combined neoadjuvant, adjuvant or radical chemoirradiation treatment with weekly cisplatin chemotherapy (40 mg/m(2)/week) in patients diagnosed with cervix cancer is a well tolerated treatment and chronic and acute toxicity is low-grade. This treatment scheme has easy compliance (AU)
RESUMEN
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Collection:
06-national
/
ES
Database:
IBECS
Main subject:
Radiotherapy
/
Adenocarcinoma
/
Antineoplastic Combined Chemotherapy Protocols
/
Uterine Cervical Neoplasms
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
Language:
En
Journal:
Clin. transl. oncol. (Print)
Year:
2009
Document type:
Article