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Increased bile resistance in Salmonella enterica mutants lacking Prc periplasmic protease
Hernández, Sara B; Ayala, Juan A; Rico-Pérez, Gadea; García-del Portillo, Francisco; Casadesús, Josep.
Affiliation
  • Hernández, Sara B; University of Sevilla. School of Biology. Department of Genetics. Sevilla. Spain
  • Ayala, Juan A; CSIC-Autonomous University of Madrid. Center of Molecular Biology Severo Ochoa. Cantoblanco. Spain
  • Rico-Pérez, Gadea; National Center of Biotechnology (CNB)-CSIC. Madrid. Spain
  • García-del Portillo, Francisco; National Center of Biotechnology (CNB)-CSIC. Madrid. Spain
  • Casadesús, Josep; University of Sevilla. School of Biology. Department of Genetics. Sevilla. Spain
Int. microbiol ; 16(2): 87-92, jun. 2013. ilus, tab
Article in English | IBECS | ID: ibc-126423
Responsible library: ES1.1
Localization: BNCS
ABSTRACT
Prc is a periplasmic protease involved in processing of penicillin-binding protein 3 (PBP3). Lack of Prc suppresses bile sensitivity in Dam-, Wec-, PhoP-, DamX-, and SeqA- mutants of Salmonella enterica, and increases bile resistance in the wild type. Changes in the activity of penicillin binding proteins PBP3, PBP4, PBP5/6 and PBP7 are detected in a Prc-background, suggesting that peptidogly can remodeling might contribute to bile resistance (AU)
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Collection: National databases / Spain Health context: Neglected Diseases Health problem: Neglected Diseases / Zoonoses Database: IBECS Main subject: Peptide Hydrolases / Salmonella enterica / Periplasmic Proteins Limits: Humans Language: English Journal: Int. microbiol Year: 2013 Document type: Article Institution/Affiliation country: CSIC-Autonomous University of Madrid/Spain / National Center of Biotechnology (CNB)-CSIC/Spain / University of Sevilla/Spain
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Collection: National databases / Spain Health context: Neglected Diseases Health problem: Neglected Diseases / Zoonoses Database: IBECS Main subject: Peptide Hydrolases / Salmonella enterica / Periplasmic Proteins Limits: Humans Language: English Journal: Int. microbiol Year: 2013 Document type: Article Institution/Affiliation country: CSIC-Autonomous University of Madrid/Spain / National Center of Biotechnology (CNB)-CSIC/Spain / University of Sevilla/Spain