Pulmonary computed tomography scan findings in chronic granulomatous disease
Allergol. immunopatol
; 42(5): 444-448, sept.-oct. 2014. ilus, tab
Article
in English
| IBECS
| ID: ibc-127279
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
BACKGROUND:
Chronic granulomatous disease is a phagocyte defect, characterised by recurrent infections in different organs due to a defect in NADPH oxidase complex. This study was performed to investigate pulmonary problems of CGD in a group of patients who underwent computed tomography (CT) scan.METHODS:
Computed tomography scan was performed in 24 patients with CGD. The findings of the CT scan were documented in all of these patients.RESULTS:
Areas of consolidation and scan formation were the most common findings, which were detected in 79% of the patients. Other abnormalities in order of frequencies were as follows small pulmonary nodules (58%); mediastinal lymphadenopathy (38%); pleural thickening (25%); unilateral hilar lymphadenopathy (25%); axillary lymphadenopathy (21%); bronchiectasis (17%); abscess formation (17%); pulmonary large nodules or masses (8%); and free pleural effusion (8%).CONCLUSION:
The pulmonary CT scans of the patients with CGD demonstrated a variety of respiratory abnormalities in the majority of the patients. While recurrent respiratory infections and abscesses are considered as prominent features of CGD, early diagnosis and precise check-up of the respiratory systems are needed to prevent further pulmonary complicationsRESUMEN
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Tomography, X-Ray Computed
/
Granulomatous Disease, Chronic
Type of study:
Diagnostic study
/
Screening study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Allergol. immunopatol
Year:
2014
Document type:
Article
Institution/Affiliation country:
Children's Medical Center/Iran
/
Shahid Beheshti University of Medical Sciences/Iran