Intimal-medialthickness and carotid arteries lumen in irradiated patients for head and neck cancer: preliminary data of an observational study
Clin. transl. oncol. (Print)
; 15(10): 861-864, oct. 2013. tab, ilus
Article
in English
| IBECS
| ID: ibc-127512
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
OBJECTIVES:
To investigate the effect of external beam radiotherapy (EBRT) for head and neck cancer (HNC) the intimal-medial thickness (IMT) and the lumen of the carotid artery.METHODS:
Patients with HNC and an indication for EBRT were enrolled. A carotid artery color Doppler examination was performed before and 6 and 12 months after EBRT.RESULTS:
From 2008 to 2011, 50 patients were enrolled. The mean carotid IMT was 0.9 vs. 1.02 mm before and 6 months after EBRT, respectively (p = 0.0001). The common carotid artery lumen was narrowed without statistical significance, 6 months after EBRT (p = 0.3). 1 year from EBRT, the IMT increase and the lumen reduction were statistically significant (p = 0.001, p = 0.01, respectively). Neurological events (stroke or TIA) were not observed.CONCLUSIONS:
Our data showed a significant IMT increase 6 months from EBRT without a corresponding narrowing of the common carotid lumen while a significant increase 12 months after EBRT (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Radiation Injuries
/
Carotid Arteries
/
Carotid Artery Diseases
/
Tunica Media
/
Carotid Intima-Media Thickness
/
Head and Neck Neoplasms
Type of study:
Etiology study
/
Evaluation study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2013
Document type:
Article
Institution/Affiliation country:
CROB+Italy