Incidence, clinical outcomes, and therapeutic approaches of capsule endoscopy-related adverse events in a large study population
Rev. esp. enferm. dig
; 107(12): 745-752, dic. 2015. tab, ilus
Article
in English
| IBECS
| ID: ibc-146742
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
INTRODUCTION:
Capsule endoscopy (CE) has become a first-line tool for small bowel (SB) examination. However, adverse events (AEs), such as CE retention or aspiration, may occur. The aims of this study were to evaluate incidence, clinical outcomes and therapeutic approaches of CE-related AEs in the largest series published to date.METHODS:
Data from 5428 procedures performed at 12 institutions between August 2001 and January 2012 were retrospectively analyzed. Baseline patient characteristics; procedure; type, localization and symptoms before/after AEs; previous patency tests performed; therapeutic management and patient's outcome were recorded.RESULTS:
The overall incidence of CE-related AEs was 1.9% 2.0% for SB, 0.9% for esophageal and 0.5% for colon CE. The incidence of capsule retention was significantly higher than capsule aspiration (1.87% vs. 0.003%; p < 0.05), in patients suffering from inflammatory bowel disease (IBD) than in obscure GI bleeding (OGIB) (3.3% vs. 1.5%; p < 0.05) and in patients with the combination of nausea/vomiting, abdominal pain and distension. The SB was the most frequent localization of retention (88.2%). The use of patency tests -except for Patency© capsule- before CE was not a good predictor for AEs. Most of the patients with AEs developed no or mild symptoms (97%) and were managed by non-surgical methods (64.4%).CONCLUSIONS:
CE-related AEs are uncommon and difficult to predict by imagiological examinations. SB retention, that is usually asymptomatic, is the most frequent AE. In absence of symptoms, non-surgical management of CE-related AEs is recommended
Full text:
Available
Collection:
National databases
/
Spain
Health context:
Neglected Diseases
Health problem:
Diarrhea
Database:
IBECS
Main subject:
Capsule Endoscopy
/
Capsule Endoscopes
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
Rev. esp. enferm. dig
Year:
2015
Document type:
Article
Institution/Affiliation country:
Complejo Hospital de Navarra/Spain
/
Complejo Hospitalario de Toledo/Spain
/
Hospital Clínic/Spain
/
Hospital General Universitario Gregorio Marañon/Spain
/
Hospital General Universitario Morales Messeguer/Spain
/
Hospital Universitario Marqués de Valdecilla/Spain
/
Hospital Universitario Virgen Macarena/Spain
/
Hospital Universitario Virgen de la Arrixaca/Spain
/
Hospital Universitario y Politécnico La Fe/Spain
/
Hospital Virgen de las Nieves/Spain