Predictive factors of small bowel patency in Crohns disease patients
Rev. esp. enferm. dig
; 108(2): 65-70, feb. 2016. tab, graf
Article
in English
| IBECS
| ID: ibc-148361
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Background:
Patency capsule was developed to avoid small bowel video capsule endoscopy retention, namely in patients with Crohns disease.Aims:
To evaluate the predictive factors of small bowel patency in Crohns disease patients. Patients andmethods:
Retrospective analysis including 151 Crohns disease patients submitted to patency capsule (Agile® Patency Capsule) from 2011 to 2012. Patients that excreted the intact patency capsule were classified as having a patent small bowel (without patency capsule retention), other patients were considered to have negative patency of the small bowel (patency capsule retention).Results:
Patients had a mean age of 41±14 years, 54% were female and 25% had been previously submitted to surgery. Stricturing disease was seen in 20% of cases and penetrating disease in 16% of cases. Left-sided colonic lesions and ileal strictures were observed at colonoscopy in 13% and 9% of patients, respectively. In our sample, 28% of patients had negative patency of the small bowel (patency capsule retention). In multivariate analysis, independent factors that were associated with negative patency of the small bowel in Crohns disease patients were structuring (OR 10.16, p < 0.001) and penetrating phenotypes (OR 11.73, p = 0.001), left-sided colonic lesions (OR 3.77, p = 0.038), ileal stricture (OR 9.76, p = 0.003); previous intestinal surgery was found to be protective (OR 0.16, p = 0.006).Conclusions:
Stricturing or penetrating disease, ileal strictures, no previous surgery and left-sided colonic lesions were the factors associated with negative small bowel patency in Crohns disease patients (AU)RESUMEN
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Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Crohn Disease
/
Intestine, Small
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Rev. esp. enferm. dig
Year:
2016
Document type:
Article
Institution/Affiliation country:
Centro Hospitalar São João/Portugal
/
University of Porto/Portugal