Clinical target volume in postoperative radiotherapy for gastric cancer: identification of major difficulties and controversies
Clin. transl. oncol. (Print)
; 18(5): 480-488, mayo 2016. tab, ilus
Article
in English
| IBECS
| ID: ibc-151181
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Purpose:
To identify the main difficulties in postoperative clinical target volume (CTV) delineation in gastric cancer (GC).Methods:
Before and after a training course, 20 radiation oncology residents were asked to delineate the CTV for the postoperative GC case on four computed tomography scans dome of the diaphragm, anterior abdominal wall, duodenal stump and porta hepatis level, and to determine the lower CTV border. CTV volume was reconstructed from requested planar contours. Area of intersection (AI) for each requested scan and volume of intersection (VI), defined as the overlap of delineated area/volume with respective reference area (RA)/reference volume (RV) proposed by the senior radiation oncologist, were computed. The degree of agreement between the reference and participants contours was quantified using the Concordance Index (CI) AI/RA 9 100 % or VI/RV 9 100 %. The lower CTV border was analyzed separately. Pre- and post-training CIs were compared. A questionnaire investigated the difficulties with contouring.Results:
Mean CI value was the lowest for the dome of the diaphragm (24 % pre-training, 35 % post-training) and for the duodenal stump (49 % pre-training, 61 % post-training). Mean CI for the CTV volume was 49 % pre-training and 59 % post-training, p = 0.39. Mean distance from the reference to the participants lower CTV borders was 2.73 cm pre-training and 2.0 cm post-training, p = 0.71. In a questionnaire, 75 % of respondents indicated the elective nodal area as the main difficulty.Conclusions:
Delineation of the dome of the diaphragm and the duodenal stump, as yet not recognized as the source of variation, should be addressed in the international consensus guidelines and clarified (AU)RESUMEN
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Radiotherapy
/
Stomach Neoplasms
/
Diaphragm
/
Radiotherapy, Adjuvant
/
Duodenum
Type of study:
Diagnostic study
/
Practice guideline
/
Qualitative research
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2016
Document type:
Article
Institution/Affiliation country:
Greater Poland Cancer Center/Poland
/
Ministry of the Interior and Warmian & Mazurian Oncology Centre/Poland
/
Regional Oncology Center/Poland
/
Subcarpathian Cancer Center/Poland
/
West Pomeranian Oncology Center/Poland