Comparative study between two different staging systems (AJCC TNM VS BALLANTYNES) for mucosal melanomas of the Head & Neck
Med. oral patol. oral cir. bucal (Internet)
; 21(4): e425-e430, jul. 2016. tab, graf
Article
in English
| IBECS
| ID: ibc-155297
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
BACKGROUND:
Mucosal melanoma (MM) of head and neck (H&N) is a rare entity with a quite poor prognosis. Ballantyne's staging system has been commonly used since 1970. In the 7th edition of the AJCC Staging Manual a new chapter for the staging of TNM Classification system for mucosal melanoma (MM) of the head and neck (H&N) has been introduced to reflect the particularly aggressive biological behavior of this neoplasm. The aim of this study was to analyze and compare among Ballantyne's staging system vs TNM H&N in terms of overall survival (OS) and disease-free survival (DFS) in a consecutive population of patients with MM in a cancer centre. MATERIAL ANDMETHODS:
Descriptive analysis of demographic, clinical and pathological variables of MM of the Head & Neck were performed. We compared the survival curves for both systems according to the Kaplan-Meier method using the Log-rank test.RESULTS:
An up-staging migration effect from Ballantyne's localized disease to moderately and very advanced disease according to AJCC staging system. The 5-year DFS and OS for Ballantyne's Localized Disease and AJCC Stage III were 31% and 36% vs. 47% and 50%, respectively. For locoregional disease the 5-year DFS / OS were 5% / 10% for Bal-lantyne's system vs. 13.8% / 17.8% and 0 / 0% for AJCC Stages IVA and IVB, respectively.CONCLUSIONS:
In this series, the TNM staging system for MM of the H&N predicted better the prognosis of the disease when comparing with Ballantyne's system
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Melanoma
/
Mouth Mucosa
/
Neoplasm Staging
Type of study:
Practice guideline
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Med. oral patol. oral cir. bucal (Internet)
Year:
2016
Document type:
Article
Institution/Affiliation country:
Hospital General Manuel Gea Gonzalez/México
/
Hospital Primero de Octubre/México
/
Instituto Nacional de Cancerologia México/México
/
Universidad Autónoma Metropolitana/México
/
Universidad Nacional Autónoma de México/México