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Body mass index cutoff point estimation as obesity diagnostic criteria in Down syndrome adolescents / Estimación del punto de corte del índice de masa corporal como criterio diagnóstico de obesidad en adolescentes con síndrome de Down
Samur-San-Martin, Juan Eduardo; Moreira Gonçalves, Ezequiel; Bertapelli, Fabio; Mendes, Roberto Teixeira; Guerra-Júnior, Gil.
Affiliation
  • Samur-San-Martin, Juan Eduardo; Center for Investigation in Pediatrics (CIPED). Laboratory of Growth and Development. Brazil
  • Moreira Gonçalves, Ezequiel; Center for Investigation in Pediatrics (CIPED). Laboratory of Growth and Development. Brazil
  • Bertapelli, Fabio; s.af
  • Mendes, Roberto Teixeira; State University of Canpinas (UNICAMP). School of Medicine. Department of Pediatrics. Campinas. Brazil
  • Guerra-Júnior, Gil; Center for Investigation in Pediatrics (CIPED). Laboratory of Growth and Development. Brazil
Nutr. hosp ; 33(5): 1090-1094, sept.-oct. 2016. tab
Article in English | IBECS | ID: ibc-157276
Responsible library: ES1.1
Localization: BNCS
ABSTRACT

Introduction:

Adolescents with Down syndrome (DS) show high rate of overweight and tend to accumulate high amount of fat compared to the same people without the syndrome.

Objective:

To estimate the cutoff point of the Body Mass Index (BMI) for the diagnosis of obesity in adolescents with DS according to different references for BMI in relation to the percentage of body fat (%BF) measured by dual-energy X-ray absorptiometry (DXA).

Methods:

The sample was composed of 34 adolescents with DS (aged 10 to 17 years old). BMI was evaluated according to the references of the International Obesity Task Force (IOTF), the World Health Organization (WHO) for the general population, and Myrelid et al. and Styles et al. for people with DS. The %BF was assessed by whole body DXA and classified according to National Health And Nutrition Examination Survey (NHANES, 2011).

Results:

The boys were significantly taller than the girls and this %BF higher than boys. All references who have used BMI to assess obesity was positively associated with %BF measured by DXA in the diagnosis of obesity. Using the ROC curve in relation to %BF by DXA, all references showed high sensitivity, but the z-score of BMI by WHO showed better specificity, with the value of the accuracy of 0.82 for the cutoff point above 2.14.

Conclusions:

All the references used for the diagnosis of obesity were associated with %BF measured by DXA, and the cutoff point of z-scores above 2.14 by WHO showed better specificity (AU)
RESUMEN

Introducción:

adolescentes con síndrome de Down (SD) muestran alta tasa de sobrepeso y tienden a acumular gran cantidad de grasa en comparación con los adolescentes sin el síndrome.

Objetivo:

estimar el punto de corte del índice de masa corporal (IMC) para el diagnóstico de obesidad en adolescentes con SD de acuerdo con las diferentes referencias para el IMC en relación con el porcentaje de grasa corporal (%GC) obtenido por el absorciometría con rayos X de doble energía (DXA).

Métodos:

la muestra se compone de 34 adolescentes con SD (10 a 17 años). El IMC se evaluó de acuerdo con las referencias de la International Obesity Task Force (IOTF), Organización Mundial de la Salud (OMS) para la población general, y Myrelid et al. y Estyles et al. para personas con SD. El %GC fue evaluado por DXA y clasificado según NHANES (2011).

Resultados:

los niños fueron significativamente más altos que las niñas, y estas con mayor %GC que los niños. Todas las referencias que han utilizado el IMC se asociaron positivamente con el %GC medido por DXA en el diagnóstico de la obesidad. Utilizando la curva ROC en relación con %GC por DXA todas las referencias mostraron alta sensibilidad, pero el score-z del IMC por la OMS mostró mejor especificidad, con el valor de exactitud de 0,82 para el punto de corte por encima de 2,14.

Conclusiones:

todas las referencias utilizadas para el diagnóstico de obesidad se asociaron con el %GC medido por DXA, y el punto de corte del score-z por encima de 2,14 por la OMS mostró mejor especificidad (AU)
Subject(s)

Full text: Available Collection: National databases / Spain Health context: SDG3 - Health and Well-Being Health problem: Target 3.8 Achieve universal access to health Database: IBECS Main subject: Body Mass Index / Down Syndrome / Adiposity / Obesity Type of study: Diagnostic study / Prognostic study Limits: Adolescent / Female / Humans / Male Language: English Journal: Nutr. hosp Year: 2016 Document type: Article Institution/Affiliation country: Center for Investigation in Pediatrics (CIPED)/Brazil / State University of Canpinas (UNICAMP)/Brazil

Full text: Available Collection: National databases / Spain Health context: SDG3 - Health and Well-Being Health problem: Target 3.8 Achieve universal access to health Database: IBECS Main subject: Body Mass Index / Down Syndrome / Adiposity / Obesity Type of study: Diagnostic study / Prognostic study Limits: Adolescent / Female / Humans / Male Language: English Journal: Nutr. hosp Year: 2016 Document type: Article Institution/Affiliation country: Center for Investigation in Pediatrics (CIPED)/Brazil / State University of Canpinas (UNICAMP)/Brazil
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