SEOM Clinical Guideline for treatment of muscle-invasive and metastatic urothelial bladder cancer (2016)
Clin. transl. oncol. (Print)
; 18(12): 1197-1205, dic. 2016. tab
Article
in English
| IBECS
| ID: ibc-158635
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
The goal of this article is to provide recommendations for the diagnosis and treatment of muscle-invasive and metastatic bladder cancer. The diagnosis of muscle-invasive bladder cancer is made by pathologic evaluation after transurethral resection. Recently, a molecular classification has been proposed. Staging of muscle-invasive bladder cancer must be done by computed tomography scans of the chest, abdomen and pelvis and classified on the basis of UICC system. Radical cystectomy and lymph node dissection are the treatment of choice. In muscle-invasive bladder cancer, neoadjuvant chemotherapy should be recommended in patients with good performance status and no renal function impairment. Although there is insufficient evidence for use of adjuvant chemotherapy, its use must be considered when neoadjuvant therapy had not been administered in high-risk patients. Multimodality bladder-preserving treatment in localized disease is an alternative in selected and compliant patients for whom cystectomy is not considered for clinical or personal reasons. In metastatic disease, the first-line treatment for patients must be based on cisplatin-containing combination. Vinflunine is the only drug approved for use in second line in Europe. Recently, immunotherapy treatment has demonstrated activity in this setting (AU)
RESUMEN
No disponible
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Carcinoma, Transitional Cell
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Cystectomy
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Muscle Neoplasms
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Gallbladder Neoplasms
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Immunotherapy
Type of study:
Practice guideline
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Prognostic study
Limits:
Female
/
Humans
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Male
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2016
Document type:
Article
Institution/Affiliation country:
Althaia/Spain
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Complejo Hospitalario de Navarra/Spain
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Complexo Hospitalario Universitario de Ourense/Spain
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Complexo Hospitalario Universitario de Vigo/Spain
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Germans Trias i Pujol University Hospital/Spain
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Hospital Universitario La Paz/Spain
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Hospital Universitario Lucus Augusti/Spain
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Hospital Universitario San Carlos/Spain
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Hospital Universitario Son Espases/Spain
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Parc Taulí Sabadell Hospital Universitari/Spain